Urine test may more accurately detect prostate cancer

Urine test may more accurately detect prostate cancer

A urine sample may be able to detect prostate cancer and save lives, research supported by the Irish Cancer Society has shown. Researchers at University College Dublin have led the development of the simple urine test, which is 70% more specific for prr cent more specific for prostate cancer, when compared to blood tests currently used by doctors. If the new “epiCaPture” test is further validated it could help to more accurately identify which men do or don’t need invasive tests. This means that many men could be spared harsh treatments that often have long-term side effects. The test could also help to identify aggressive prostate cancer early, so that more patients can be potentially cured of their cancer. The research was part of an international collaboration led by Dr Antoinette Perry, assistant professor of cell biology and genetics at the UCD School of Biology and Environmental Science and the UCD Conway Institute. Dr Perry and her team including PhD students Eve O’Reilly and Irish Cancer Society funded researcher Alexandra Tuzova said, while early detection was vital, current tests to detect prostate cancer were not entirely accurate. She said “over the last four years our research team at University College Dublin has worked with doctors, nurses, patients and other scientists from around Ireland, the UK, USA and Canada to study urine from almost 500 men. We showed that almost 90 percent of men with aggressive prostate cancer have changes in their DNA that we could find in their urine. “These changes were absent in healthy men and men with non-aggressive disease. If we can replicate these findings, our research could contribute to a new, more accurate test to help catch aggressive prostate cancer and save lives from this disease.”